Hormonal abnormalities in azoospermic men in Kano, Northern Nigeria.

نویسندگان

  • M A Emokpae
  • P O Uadia
  • A Z Mohammed
  • A Omale-Itodo
چکیده

BACKGROUND & OBJECTIVES We undertook this study to observe the pattern of hormonal abnormalities and testicular pathology in azoospermic male Africans in Kano, Northern Nigeria. METHODS Eighty consecutive azoospermic infertile males attending fertility clinic in Aminu Kano Teaching Hospital, Kano, were selected for the study. Their semen were analyzed three times at eight weeks interval, after which serum follicle stimulating hormone (FSH), luteinizing hormone (LH), testosterone and prolactin were assayed in serum samples, and histological examination of testicular biopsies done. RESULTS Of the 80 subjects studied, 32 (40%) had abnormal hormonal levels, 48 (60%) had normal hormonal values and 36 (45%) had testicular pathology. INTERPRETATION & CONCLUSION Endocrinopathies are common in azoospermia. Their contribution to male factor infertility cannot be overemphasized. The main reason for the endocrinopathies is not known but environmental factors, endocrine disruptors and genetic polymorphism have been suggested to be contributory.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Male infertility and endocrinopathies in Kano, Northwestern Nigeria.

BACKGROUND/OBJECTIVE Endocrinologic disorders and infertility are common all over the world; the prevalence of infertility is high in sub-Saharan Africa. Several authors have suggested that the increased incidence of infertility in Africa is due to high prevalence of sexually transmitted diseases. To evaluate the contributions of endocrine abnormalities to infertility in the male in Kano, North...

متن کامل

Predictors of Safer Conception Practices Among HIV-Infected Women in Northern Nigeria

Background Persons living with HIV often face discrimination in safe sex and reproductive choices, especially in lowresource settings. This study assessed fertility desires and intentions, risk perception and correlates of ever use of at least one safer conception method among HIV-infected women attending a tertiary health facility ...

متن کامل

Chromosomal Abnormalities in Iranian Infertile Males who are Candidates for Assisted Reproductive Techniques

Background The present study offers our contribution on the topic by a retrospective analysis of the prevalence of chromosomal abnormalities in a population of Iranian infertile men attending assisted reproduction programs. MaterialsAndMethods Cytogenetic analysis was performed according to standard methods on cultured cells obtained from the patient peripheral blood. In all, 874 files belongin...

متن کامل

P-3: Complete Reproductive Hormonal Study in Nonobstructive Azoospermic (NOA) Patients for Determining Reliable Markers of The Presence of Spermatozoa in Their Biopsies

Background: Various hormone tests of the presence of spermatozoa on testicular sperm extraction (TESE) in azoospermic men have been investigated. Because of its clinical importance, we conducted this study to evaluate complete reproductive serum hormone levels in nonobstructive azoospermic (NOA) patients for determining markers which can predict the spermatogenesis. Materials and Methods: Seven...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Indian journal of medical research

دوره 124 3  شماره 

صفحات  -

تاریخ انتشار 2006